VMA (Vanillylmandelic Acid), 24-Hour Urine with Creatinine QVMA24

Method(s) High Performance Liquid Chromatography (HPLC)
Synonym Vanillymandelic Acid w/ Creatinine, VMA, 24 Hr Urine w/ Creatinine
Specimen Required
Collect

24-hour Urine.

Transport

10 mL aliquot from a 24-hour urine that has been preserved with 25 mL 6N HCI, collected in a plastic 24-hour urine container (Min: 5 mL).

Preserved urine: Ambient

Unpreserved urine: Frozen

* Collection Instructions *

  • Collect 24-hour urine with 25 mL 6N HCI to maintain a pH less than or equal to 3.
  • If no preservative is used, specimen must be stored refrigerated during collection but shipped frozen and pH must be less than or equal to 6.
Remarks

Patient Preparation:

  • It is preferable for patient to be off medications for three days prior to collection.
  • However, common antihypertensive (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference.
  • Patient should avoid alcohol, coffee, tea, tobacco (including use of nicotine patch), bananas, citrus fruits and strenuous exercise prior to collection.
Stability

Ambient: 10 days

Refrigerated: Unacceptable

Frozen: 30 days

Unacceptable Conditions
  • Preserved urine received refrigerated with pH greater than 3
  • Unpreserved urine received frozen with pH less than 6
Schedule Mon-Sat
CPTCode 82570, 84585
Notes Performing Laboratory-Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
Preferred Specimen Collection Device(s)
Reference Interval
 
VMA, 24-Hour Urine
Less than 3 YearsNot established
3-8 YearsLess than or equal to 2.3 mg/24 hours
9-12 YearsLess than or equal to 3.4 mg/24 hours
13-17 YearsLess than or equal to 3.9 mg/24 hours
AdultsLess than or equal to 6.0 mg/24 hours
Creatinine, 24-Hour Urine
Less than 3 YearsNot established
3-8 Years0.10-0.80 g/24 h
9-12 Years0.20-1.40 g/24 h
13-17 Years0.40-1.90 g/24 h
Greater than 17 Years0.50-2.15 g/24 h
No Appointment Necessary
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11 Patient Service Centers in Central New York.

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