Porphobilinogen, Quantitative, 24-Hour Urine QPOR24

Method(s) Chromatography/Mass Spectrometry
Synonym PBG
Specimen Required
Collect

24-hour Urine.

Transport

2 mL from 24-hour urine containing sodium carbonate.

PROTECT FROM LIGHT.

* Collection Instructions *

  • 24-hour urine, collection should be adjusted to a pH of 6-7 with 5 g sodium carbonate (Na2CO3).
  • Add the sodium carbonate at the start of the collection.
  • The urine should be refrigerated and protected from light during collection.
  • Whenever possible, the specimen should be collected during an acute episode because porphobilingen (PBG) may decrease rapidly upon remission.
  • PBG may also degrade when samples are exposed to UV light for extended periods, or are transported at ambient temperature.
  • If an amber collection jug/urine cup is not available, the sample must be protected from light by completely wrapping the container in aluminum foil.
  • Twenty-four hour specimens should be refrigerated and protected from UV light during collection.
  • PBG is most stable at pH 6-7, but sample may be sent with or without preservative.
  • All results should be interpreted in the context of clinical findings, relevant history, and other laboratory data.
Stability

Ambient: Unacceptable

Refrigerated: 7 days (pH 6-7)

Frozen: 30 days (pH 6-7)

Unacceptable Conditions

Not protected from light

Schedule Tue, Thu, Sat pm; Report available: 4 days
CPTCode 84110
Notes Performing Laboratory-Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
Preferred Specimen Collection Device(s)
Reference Interval

Less than or equal to 17 Years: Not established
Greater than or equal to 18 Years: Less than 0.34 / 24 h

 

No Appointment Necessary
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12 Patient Service Centers in Central New York.

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