Itraconazole, Quantitative by LC-MS/MS ITRACO

Method(s) Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Specimen Required
Collect

One 5 mL plain red top tube. Alxo acceptable: lavender (EDTA) or green (sodium or lithium heparin) top tubes.

Transport 1 mL serum frozen. (Min: 0.6 mL)
Remarks

Timing of specimen collection: Pre-dose (trough) draw - at steady state concentration.

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: 6 months

Unacceptable Conditions

Whole blood. Gel separator tubes, Light Blue (citrate), or Yellow (SPS or ACD solution).

Schedule Tue, Thu, Sat
Billing Code 5011295
CPTCode 80299
Preferred Specimen Collection Device(s)
Reference Interval
 
 Therapeutic Ranges
Itraconazole (trough) - Localized Infection
Greater than 0.5 µg/mL
Itraconazole (trough) - Systemic InfectionGreater than 1.0 µg/mL
HydroxyitraconazoleNo therapeutic range established

Total concentrations for itraconazole and hydroxyitraconazole should not exceed 10 µg/mL.

No Appointment Necessary
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11 Patient Service Centers in Central New York.

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