Imipramine & Desipramine IMIP
| Method(s) | Quantitative Liquid Chromatography - Tandem Mass Spectrometry |
|---|---|
| Specimen Required | |
| Collect | One 6 mL plain red top tube. Also acceptable: lavender (EDTA) or pink (K2EDTA) top tubes. |
| Transport | 1 mL serum or plasma refrigerated (Min: 0.5 mL). Separate serum/plasma from cells ASAP or within 2 hours of collection. |
| Remarks | Patient preparation: Pre-dose (trough) draw - At steady state concentration. |
| Stability | After separation from cells: 5 days; Refrigerated: 2 weeks; Frozen: 6 months |
| Unacceptable Conditions | Whole blood, separator tubes, light blue top (citrate), or yellow top (SPS or ACD solution) tubes. |
| Schedule | Mon, Wed, Fri |
| Billing Code | 5011531 |
| CPTCode | 80335 (Alt code: G0480) |
| Preferred Specimen Collection Device(s) | |
| Reference Interval | |
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Therapeutic Range: Total (Imipramine & Desipramine): 150-300 ng/mL Toxic: Greater than 500 ng/mL |
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