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QuantiFERON -TB Gold Plus (QTF4) Assay Offered Locally

Monday, June 7, 2021

Effective June 1, 2021, Laboratory Alliance of Central New York will offer the QuantiFERON -TB Gold Plus (QTF4) assay. It will be performed locally at our Operations Center laboratory. The assay is an interferon-γ (IFN-y) release assay performed on the Diasorin Liaison XL platform using Qiagen antigen-coated tubes.

The QFT4 assay is an indirect screening assay that detects IFN-y cytokine release by CD4+ and CD8+ cells when a patient’s blood is incubated with tuberculosis (TB) antigens (ESAT-6 and CFP-10). The assay results are not affected by previous Bacillus Calmette and Guérin (BCG) vaccinations. This assay should not be used as the sole basis for diagnosing active or latent TB infection and results must be interpreted in conjunction with risk assessment, radiography and other medical and diagnostic evaluations.

 

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