Clozapine CLOZAP
| Method(s) | Quantitative Liquid Chromatography/Tandem Mass Spectrometry |
|---|---|
| Specimen Required | |
| Collect | One 6 mL plain red top tube. Also acceptable: lavender (EDTA) or pink (K2EDTA) top tubes. |
| Transport | 1 mL serum or plasma at 2-8°C. (Min: 0.5 mL) |
| Remarks | Separate serum or plasma from cells within 2 hours of collection. |
| Stability | After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 3 months |
| Unacceptable Conditions | Whole blood, separator tubes, light blue (citrate), or yellow (SPS or ACD Solution) top tubes. |
| Schedule | Daily |
| Billing Code | 5011713 |
| CPTCode | 80159 |
| Notes | Patient Prep: Timing of specimen; collection: pre-dose (trough) draw at steady state concentration |
| Preferred Specimen Collection Device(s) | |
| Reference Interval | |
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Therapeutic range not well established.
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