Myelin Associated Glycoprotein (MAG) Antibody, IgM MAGM
Method(s) | Enzyme-Linked Immunosorbent Assay |
---|---|
Specimen Required | |
Collect | One 5 mL gold (SST) top tube. |
Transport | 1 mL serum at 2-8°C. (Min: 0.5 mL) |
Remarks | Separate serum from cells ASAP. |
Stability | Ambient: 48 hours; Refrigerated: 2 weeks; (After cell separation) Frozen: 1 year |
Unacceptable Conditions | Heat inactivated, hemolyzed, severely lipemic, or contaminated specimens. Urine. |
Schedule | Tue, Thu, Sat |
Billing Code | 5011111 |
CPTCode | 83516 |
Preferred Specimen Collection Device(s) | |
Reference Interval | |
Less than 1000 TU Detection of IgM autoantibody against myelin associated glycoprotein (MAG) suggests active demyelination in peripheral neuropathy. The possibility of MAG antibody involvement in a suspected neuropathy may essentially be ruled out if a MAG IgM negative result is obtained. Detection of MAG IgM antibody by ELISA using human MAG (100 kD) antigen is significantly more sensitive and specific than MAG Western blot and IFA assay using primate antigen. |