Itraconazole, Quantitative by LC-MS/MS ITRACO
| Method(s) | Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry | |||||||||
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| Specimen Required | ||||||||||
| Collect | One 5 mL plain red top tube. Alxo acceptable: lavender (EDTA) or green (sodium or lithium heparin) top tubes. |
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| Transport | 1 mL serum frozen. (Min: 0.6 mL) | |||||||||
| Remarks | Timing of specimen collection: Pre-dose (trough) draw - at steady state concentration. |
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| Stability | After separation from cells: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: 6 months |
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| Unacceptable Conditions | Whole blood. Gel separator tubes, Light Blue (citrate), or Yellow (SPS or ACD solution). |
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| Schedule | Tue, Thu, Sat | |||||||||
| Billing Code | 5011295 | |||||||||
| CPTCode | 80299 | |||||||||
| Preferred Specimen Collection Device(s) | ||||||||||
| Reference Interval | ||||||||||
Total concentrations for itraconazole and hydroxyitraconazole should not exceed 10 µg/mL. |
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